Nuclear Magnetic Resonance Spectroscopy (NMR) enables molecular level analysis of organic compounds. NMR absorption spectra are generated by certain magnetic nuclei placed in a strong magnetic field, when excited by RF pulses. The spectral peaks correspond to resonant RF frequencies characterizing the type of nuclei and bonding environment. ... Read More
Average 30% Cost Savings
100% Confidentiality Guarantee
Free, No-obligation Consultation
100% Customer Satisfaction
TRUSTED BY ENGINEERS FROM
Nuclear Magnetic Resonance Spectroscopy (NMR)
Nuclear Magnetic Resonance Spectroscopy (NMR) is used for the compositional analysis of organic materials. NMR utilizes the fact that certain atomic nuclei have magnetic moments and can interact with externally applied magnetic fields. These typically have odd mass numbers, such as 1H, 13C, 19F, 29Si, 15N. When subjected to a strong constant external magnetic field, these magnetic moments get aligned with (parallel) or opposed to (anti-parallel) to the applied field. The parallel orientation represents a lower energy state relative to the anti-parallel alignment. If the nuclei are now subjected to electromagnetic radiation in the Radiofrequency (RF) range, the lower energy nuclei absorb energy and at a resonant frequency, their alignment flips-over (spin-flip) to the higher energy state. The resonant frequency depends on the type of nuclei and bonding environment as well as the applied magnetic field. Hence NMR provides information on composition and structure of molecules in the sample. In NMR spectrometers, organic compounds are placed in magnetic fields ranging from about 1.4 to 18.0 tesla (T).
The NMR spectrometry procedure involves placing a sample in a strong magnetic field and then exciting the sample using pulsed Radiofrequency waves of the appropriate frequency range. At resonant frequencies, the spin-flip of various nuclei is picked up by a detector. The respective resonant frequencies and absorbance intensities are recorded as peaks in the NMR spectrum. It must be noted that NMR detects only the nuclei with magnetic moments. For example, magnetic isotopes of elements such as 1H, 13C, 19F, 29Si, 15N, yield high-resolution NMR spectra at their resonant frequencies. Hence, in a typical organic compound having Carbon backbone and covalent bonds with Hydrogen, NMR targets only the magnetic 13C nuclei and the surrounding Hydrogen atoms (Protons), to infer the structure. This process requires computer analysis, using a reference database. Proton NMR is an important form of NMR for structural analysis, since Hydrogen atoms absorb energy of different wavelengths depending on their bonding environment.
NMR can be applied to substances in liquid solution or in solid state. When NMR spectroscopy is performed on solids, it is termed Solid State NMR. Polymers and plastics are examples where Solid State NMR has been used. In such cases, magnetized Protons distort the 13C signal, which is resolved by heteronuclear dipolar decoupling (DD). In the case of liquid solutions, Deuterated solvents are used, in which all Protons have been replaced by Deuterium. This avoids signal distortion by magnetic Protons in the solvent.
Common Uses of Nuclear Magnetic Resonance Spectroscopy (NMR)
In research and Quality control for analysis of Organic compounds
Analysis of composition and structure of coal
Study of Protein structures
Compositional analysis of polymers and plastics
Advantages of Nuclear Magnetic Resonance Spectroscopy (NMR)
ASTM E572 test method covers the analysis of stainless and alloy steels by Wavelength Dispersive X-ray Fluorescence Spectrometry (WDXRF). It provides rapid, multi-element determinations with sufficient accuracy to assure product quality.
The ASTM D2674 test is a standard test method for the analysis of sulfochromate etch solutions used in the surface preparation of aluminum. The ASTM D2674 standard specifies a method for determining the efficacy of an etchant used to prepare the surface of aluminum alloys for subsequent adhesive bonding.
An immunological method for quantization of Hevea Natural Rubber (HNRL) proteins using rabbit anti-HNRL serum. Rabbits immunized with HNRL proteins react to the majority of the proteins present, and their sera have the capability to detect most if not all the proteins in HNRL.
ASTM G65 measures the resistance of metallic materials to abrasion using the dry sand/rubber wheel apparatus. The quality, durability, and toughness of the sample are determined using this test. Metallic materials are ranked in their resistance to scratching abrasion under a controlled environment.
ASTM E2141 test methods provide accelerated aging and monitoring of the performance of time-dependent electrochromic devices (ECD) integrated in insulating glass units (IGU). This test helps to understand the relative serviceability of electrochromic glazings applied on ECD.
ASTM C724 test method is used in analyzing the quality and ease of maintenance of a ceramic decoration on architectural-type glass. This test method is useful in the acknowledgment of technical standards.
Send us a request
Process for testing
STEP 01
You share material and testing requirements with us
STEP 02
You ship your sample to us or arrange for us to pick it up.
STEP 03
We deliver the test report to your email.
Just share your testing requirements and leave the rest on us!
Free, no-obligation consultation
Guaranteed confidentiality
Quick turnaround time
Hassle-free process
Let us combine our capabilities to achieve success!!