Inductively Coupled Plasma Mass Spectrometry – ICP-MS

Scope

ICP-MS uses a high-temperature inductively coupled argon plasma to atomize and ionize liquid samples containing elements, which are then introduced into the mass spectrometer for separation, identification, and quantitative analysis of the elements present. This enables simultaneous multi-element trace analysis with parts-per-trillion sensitivity across a broad range of elements.

ICP-MS analysis evaluates:

• Ultra-trace multi-element quantification in liquid, dissolved solid, and digested material samples
• Heavy metal and toxic element detection at parts-per-trillion concentration levels
• Isotopic ratio measurement and isotope dilution analysis for high-accuracy elemental quantification
• Elemental impurity profiling in pharmaceutical, electronic, and high-purity material systems
• Compliance of elemental composition against the defined material specification and purity requirements

Applications

• High-purity materials, electronic-grade chemicals, and semiconductor process fluids requiring trace elemental certification
• Pharmaceutical elemental impurity analysis per ICH Q3D and USP guidelines
• Environmental water, soil, and sediment sample analysis for heavy metal and toxic element quantification
• Food, beverage, and dietary supplement trace element and heavy metal screening
• Failure analysis and contamination investigation programs requiring ultra-trace elemental identification

Benefits

• Delivers ultra-sensitive multi-element trace analysis at parts-per-trillion detection levels
• Provides simultaneous full periodic table elemental coverage within a single analytical run
• Identifies trace elemental contaminants and impurities in complex sample matrices
• Delivers traceable, laboratory-certified elemental data for material
• Reduces material risk by detecting elemental impurities early in the characterization cycle