ASTM D7574 Standard Test Method for Determination of Bisphenol A in Environmental Waters by Liquid Chromatography/Tandem Mass Spectrometry
ASTM D7574 explains the determination of Bisphenol A (BPA), which is extracted from water by Solid-Phase Extraction (SPE), separated by Liquid Chromatography (LC), and detected by Tandem Mass Spectrometry (MS/MS). This method corresponds to multiple reaction monitoring mass spectrometry, whose values are measured in SI units.
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- Overview
- Scope, Applications, and Benefits
- Test Process
- Specifications
- Instrumentation
- Results and Deliverables
Overview
ASTM D7574 is a standardized analytical test method used for the qualitative and quantitative determination of Bisphenol A (BPA) in water samples. BPA is a high-volume industrial chemical widely used in the production of epoxy resins and polycarbonate polymers.
To achieve high sensitivity and selectivity, this approach employs tandem mass spectrometry (LC-MS/MS) coupled with liquid chromatography after solid-phase extraction (SPE). The test provides accurate concentration data necessary for public health protection, regulatory compliance, and environmental monitoring.
Scope, Applications, and Benefits
Scope
ASTM D7574 evaluates:
- Presence and concentration of BPA in water samples
- Trace-level detection using SPE and LC-MS/MS
- Identification through retention time and SRM transitions
- Use of surrogate and internal standards
- Quantitative reporting of BPA concentration
This method applies to environmental and drinking water testing.
Applications
- Environmental water monitoring
- Drinking water quality testing
- Industrial wastewater analysis
- Regulatory compliance testing
- Public health studies
- Plastic manufacturing quality control
- Research laboratories
Benefits
- High sensitivity and accuracy
- Reliable quantitative results
- Selective detection using MS/MS
- Minimal matrix interference
- Suitable for trace-level analysis
- Supports environmental safety programs
- Standardized testing procedure
Test Process
Sample pH Adjustment & SPE
The sample is adjusted to pH 2 and passed through a SPE cartridge to isolate BPA.
1Solvent Extraction
BPA is extracted using methyl tert-butyl ether.
2Solvent Exchange & Volume Adjustment
The extract is exchanged into methanol, concentrated, and the final volume adjusted.
3Instrumental Analysis & Identification
LC-MS/MS analysis of the sample identifies BPA.
4Technical Specifications
| Parameter | Details |
|---|---|
| Applicable Samples | Water samples |
| Sample Volume | 250 mL |
| Extraction pH | 2 |
| Final Extract Volume | 1 mL |
| Solvent Used | Methyl tert-butyl ether, methanol |
| Detection Technique | LC-MS/MS |
Instrumentation Used for Testing
- Solid-phase extraction system
- SPE cartridges
- Liquid chromatograph
- Tandem mass spectrometer (MS/MS)
- pH meter
- Concentrator/evaporator
- Analytical balance
- Data acquisition software
Results and Deliverables
- BPA concentration values
- Chromatograms
- Calibration curves
- Quality control reports
Frequently Asked Questions
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