Gas Chromatography (GC) Analysis Lab

Gas Chromatography (GC), also known as Vapor-Phase Chromatography (VPC) or Gas-Liquid Partition Chromatography (GLPC), is a type of chromatography technique used to analyze specimens that can be vaporized without decomposition. ... Read More

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    Gas Chromatography (GC) Analysis Lab

    Gas Chromatography (GC), also known as Vapor-Phase Chromatography (VPC) or Gas-Liquid Partition Chromatography (GLPC), is a type of chromatography technique used to analyze specimens that can be vaporized without decomposition. 

    In the GC unit, the gaseous or liquid sample is injected into a carrier gas (moving phase) and then passed through a stationary phase. The sample is heated and vaporized within the GC unit. The compounds in the mixture get separated and are measured by a detector. The detector converts the measured value into electrical signals which are then sent to a data processing unit. 

    The carrier gas used in GC analysis is usually inert gasses such as helium, and argon. The stationary phase is a microscopic layer of viscous liquid present on a solid surface.

    Image 01: Gas Chromatography-Mass Spectrometry

    Common Uses of Gas Chromatography (GC)

    • Determining the purity of substances.
    • Separation of components of a mixture.

    Advantages of Gas Chromatography (GC)

    • Robust technique.
    • Widely employed technique.

    Disadvantages of Gas Chromatography (GC)

    • Results are not reliable for non-volatile specimens. 
    • Materials that degrade with heat cannot be tested through GC. 

    Industrial Application of Gas Chromatography (GC)

    • Pharmaceuticals
    • FMCG
    • Forensics

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